BDBM543797 US11279703, TABLE 6.387

SMILES CC(C)(C)S(=O)(=O)Nc1cccc(c1)-c1csc2cnc(Nc3ccc4C5CNCCN5CCc4c3)nc12

InChI Key InChIKey=MTBDHPJCWYLCBM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 543797   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Aptose Biosciences

US Patent
LigandPNGBDBM543797(US11279703, TABLE 6.387)
Affinity DataIC50:  44nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent